Rechecking the Centrality-Lethality Rule in the Scope of Protein Subcellular Localization Interaction Networks

Essential proteins are indispensable for living organisms to maintain life activities and play important roles in the studies of pathology, synthetic biology, and drug design. Therefore, besides experiment methods, many computational methods are proposed to identify essential proteins. Based on the...

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Bibliographic Details
Main Authors: Peng, Xiaoqing, Wang, Jianxin, Wang, Jun, Wu, Fang-Xiang, Pan, Yi
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482623/