Foxg1-Cre Mediated Lrp2 Inactivation in the Developing Mouse Neural Retina, Ciliary and Retinal Pigment Epithelia Models Congenital High Myopia

Myopia is a common ocular disorder generally due to increased axial length of the eye-globe. Its extreme form high myopia (HM) is a multifactorial disease leading to retinal and scleral damage, visual impairment or loss and is an important health issue. Mutations in the endocytic receptor LRP2 gene...

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Bibliographic Details
Main Authors: Cases, Olivier, Joseph, Antoine, Obry, Antoine, Santin, Mathieu D., Ben-Yacoub, Sirine, Pâques, Michel, Amsellem-Levera, Sabine, Bribian, Ana, Simonutti, Manuel, Augustin, Sébastien, Debeir, Thomas, Sahel, José Alain, Christ, Annabel, de Castro, Fernando, Lehéricy, Stéphane, Cosette, Pascal, Kozyraki, Renata
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480972/