AP-1-mediated chromatin looping regulates ZEB2 transcription: new insights into TNFα-induced epithelial–mesenchymal transition in triple-negative breast cancer

The molecular determinants of malignant cell behaviour in triple-negative breast cancer (TNBC) are poorly understood. Recent studies have shown that regulators of epithelial-mesenchymal transition (EMT) are potential therapeutic targets for TNBC. In this study, we demonstrate that the inflammatory c...

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Bibliographic Details
Main Authors: Qiao, Yichun, Shiue, Chiou-Nan, Zhu, Jian, Zhuang, Ting, Jonsson, Philip, Wright, Anthony P.H., Zhao, Chunyan, Dahlman-Wright, Karin
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480717/