Hypertrophic scar contracture is mediated by the TRPC3 mechanical force transducer via NFkB activation

Wound healing process is a complex and highly orchestrated process that ultimately results in the formation of scar tissue. Hypertrophic scar contracture is considered to be a pathologic and exaggerated wound healing response that is known to be triggered by repetitive mechanical forces. We now show...

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Bibliographic Details
Main Authors: Ishise, Hisako, Larson, Barrett, Hirata, Yutaka, Fujiwara, Toshihiro, Nishimoto, Soh, Kubo, Tateki, Matsuda, Ken, Kanazawa, Shigeyuki, Sotsuka, Yohei, Fujita, Kazutoshi, Kakibuchi, Masao, Kawai, Kenichiro
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479825/