Characterizing the DNA Damage Response by Cell Tracking Algorithms and Cell Features Classification Using High-Content Time-Lapse Analysis

Characterizing the DNA Damage Response by Cell Tracking Algorithms and Cell Features Classification Using High-Content Time-Lapse Analysis

Traditionally, the kinetics of DNA repair have been estimated using immunocytochemistry by labeling proteins involved in the DNA damage response (DDR) with fluorescent markers in a fixed cell assay. However, detailed knowledge of DDR dynamics across multiple cell generations cannot be obtained using...

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Bibliographic Details
Main Authors: Georgescu, Walter, Osseiran, Alma, Rojec, Maria, Liu, Yueyong, Bombrun, Maxime, Tang, Jonathan, Costes, Sylvain V.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479605/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479605/

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