Sphingosine-1-phosphate as signaling molecule in the skin: Relevance in atopic dermatitis
Sphingolipids are essential molecules of the mammalian epidermis. Keratinocytes generate and secrete huge amounts of ceramide-precursors to the extracellular domain of the stratum corneum, where they are further metabolized to specific ceramide species. The arrangement of ceramides to well-organized...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Urban & Vogel
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479432/ |