Atomistic design of microbial opsin-based blue-shifted optogenetics tools

Microbial opsins with a bound chromophore function as photosensitive ion transporters and have been employed in optogenetics for the optical control of neuronal activity. Molecular engineering has been utilized to create colour variants for the functional augmentation of optogenetics tools, but was...

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Bibliographic Details
Main Authors: Kato, Hideaki E., Kamiya, Motoshi, Sugo, Seiya, Ito, Jumpei, Taniguchi, Reiya, Orito, Ayaka, Hirata, Kunio, Inutsuka, Ayumu, Yamanaka, Akihiro, Maturana, Andrés D., Ishitani, Ryuichiro, Sudo, Yuki, Hayashi, Shigehiko, Nureki, Osamu
Format: Online
Language:English
Published: Nature Pub. Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479019/