Thrombolytic efficacy and enzymatic activity of rt-PA-loaded echogenic liposomes

Echogenic liposomes (ELIP), that can encapsulate both recombinant tissue-type plasminogen activator (rt-PA) and microbubbles, are under development to improve the treatment of thrombo-occlusive disease. However, the enzymatic activity, thrombolytic efficacy, and stable cavitation activity generated...

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Bibliographic Details
Main Authors: Bader, Kenneth B., Bouchoux, Guillaume, Peng, Tao, Klegerman, Melvin E., McPherson, David D., Holland, Christy K.
Format: Online
Language:English
Published: Springer US 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477081/