Crystal structures of the human adiponectin receptors

Crystal structures of the human adiponectin receptors

Adiponectin stimulation of its receptors, AdipoR1 and AdipoR2, increases AMPK and PPAR activities, respectively, thereby contributing to healthy longevity as key anti-diabetic molecules. AdipoR1 and AdipoR2 were predicted to contain seven transmembrane helices with the opposite topology to G protein...

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Bibliographic Details
Main Authors: Tanabe, Hiroaki, Fujii, Yoshifumi, Okada-Iwabu, Miki, Iwabu, Masato, Nakamura, Yoshihiro, Hosaka, Toshiaki, Motoyama, Kanna, Ikeda, Mariko, Wakiyama, Motoaki, Terada, Takaho, Ohsawa, Noboru, Hato, Masakatsu, Ogasawara, Satoshi, Hino, Tomoya, Murata, Takeshi, Iwata, So, Hirata, Kunio, Kawano, Yoshiaki, Yamamoto, Masaki, Kimura-Someya, Tomomi, Shirouzu, Mikako, Yamauchi, Toshimasa, Kadowaki, Takashi, Yokoyama, Shigeyuki
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477036/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477036/

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