Optogenetic control of contractile function in skeletal muscle

Optogenetic stimulation allows activation of cells with high spatial and temporal precision. Here we show direct optogenetic stimulation of skeletal muscle from transgenic mice expressing the light-sensitive channel Channelrhodopsin-2 (ChR2). Largest tetanic contractions are observed with 5-ms light...

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Bibliographic Details
Main Authors: Bruegmann, Tobias, van Bremen, Tobias, Vogt, Christoph C., Send, Thorsten, Fleischmann, Bernd K., Sasse, Philipp
Format: Online
Language:English
Published: Nature Pub. Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475236/