BCAS2 Regulates Delta-Notch Signaling Activity through Delta Pre-mRNA Splicing in Drosophila Wing Development

BCAS2 Regulates Delta-Notch Signaling Activity through Delta Pre-mRNA Splicing in Drosophila Wing Development

Previously, we showed that BCAS2 is essential for Drosophila viability and functions in pre-mRNA splicing. In this study, we provide strong evidence that BCAS2 regulates the activity of Delta-Notch signaling via Delta pre-mRNA splicing. Depletion of dBCAS2 reduces Delta mRNA expression and leads to...

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Bibliographic Details
Main Authors: Chou, Meng-Hsuan, Hsieh, Yi-Chen, Huang, Chu-Wei, Chen, Po-Han, Chan, Shih-Peng, Tsao, Yeou-Ping, Lee, Hsiu-Hsiang, Wu, June-Tai, Chen, Show-Li
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475048/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475048/

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