Conditional U1 Gene Silencing in Toxoplasma gondii

Conditional U1 Gene Silencing in Toxoplasma gondii

The functional characterisation of essential genes in apicomplexan parasites, such as Toxoplasma gondii or Plasmodium falciparum, relies on conditional mutagenesis systems. Here we present a novel strategy based on U1 snRNP-mediated gene silencing. U1 snRNP is critical in pre-mRNA splicing by defini...

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Bibliographic Details
Main Authors: Pieperhoff, Manuela S., Pall, Gurman S., Jiménez-Ruiz, Elena, Das, Sujaan, Melatti, Carmen, Gow, Matthew, Wong, Eleanor H., Heng, Joanne, Müller, Sylke, Blackman, Michael J., Meissner, Markus
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474610/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474610/

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