CpG oligodeoxyribonucleotide 7909 enhances radiosensitivity via downregulating Oct-4 expression in radioresistant lung cancer cells
Radiotherapy is a powerful cure for local advanced non-small cell lung cancer. However, radioresistance and tumor relapse still occur in a high proportion of patients. Octamer-4 (Oct-4), a transcription factor of the POU family, plays a key role in maintaining chemoradioresistant properties and regu...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Dove Medical Press
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472028/ |