Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons

Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons

Human embryonic stem cell (hESC)-derived dopamine neurons are currently moving toward clinical use for Parkinson’s disease (PD). However, the timing and extent at which stem cell-derived neurons functionally integrate into existing host neural circuitry after transplantation remain largely unknown....

Full description

Bibliographic Details
Main Authors: Grealish, Shane, Heuer, Andreas, Cardoso, Tiago, Kirkeby, Agnete, Jönsson, Marie, Johansson, Jenny, Björklund, Anders, Jakobsson, Johan, Parmar, Malin
Format: Online
Language:English
Published: Elsevier 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471831/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471831/

Similar Items