Persistent activation of STAT3 by PIM2-driven positive feedback loop for epithelial-mesenchymal transition in breast cancer

Persistent activation of STAT3 by PIM2-driven positive feedback loop for epithelial-mesenchymal transition in breast cancer

Metastasis of breast cancer is promoted by epithelial–mesenchymal transition (EMT). Emerging evidence suggests that STAT3 is a critical signaling node in EMT and is constitutively activated in many carcinomas, including breast cancer. However, its signaling mechanisms underlying persistent activatio...

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Bibliographic Details
Main Authors: Uddin, Nizam, Kim, Rae-Kwon, Yoo, Ki-Chun, Kim, Young-Heon, Cui, Yan-Hong, Kim, In-Gyu, Suh, Yongjoon, Lee, Su-Jae
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471798/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471798/

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