Targeting the canonical Wnt/β-catenin pathway in hematological malignancies

The canonical Wnt/β-catenin pathway plays an important role in different developmental processes through the regulation of stem cell functions. In the activation of the canonical Wnt/β-catenin pathway, β-catenin protein is imported into the nucleus and activates transcription of target genes includi...

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Bibliographic Details
Main Authors: Ashihara, Eishi, Takada, Tetsuya, Maekawa, Taira
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471797/