Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds

Polygonum multiflorum Thunb. (PMT), officially listed in the Chinese Pharmacopoeia, is one of the most popular perennial Chinese traditional medicines known as He shou wu in China and East Asia, and as Fo-ti in North America. Mounting pharmacological studies have stressed out its key benefice for th...

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Main Authors: Bounda, Guy-Armel, Feng, YU
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471648/
id pubmed-4471648
recordtype oai_dc
spelling pubmed-44716482015-07-01 Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds Bounda, Guy-Armel Feng, YU Review Article Polygonum multiflorum Thunb. (PMT), officially listed in the Chinese Pharmacopoeia, is one of the most popular perennial Chinese traditional medicines known as He shou wu in China and East Asia, and as Fo-ti in North America. Mounting pharmacological studies have stressed out its key benefice for the treatment of various diseases and medical conditions such as liver injury, cancer, diabetes, alopecia, atherosclerosis, and neurodegenerative diseases as well. International databases such as PubMed/Medline, Science citation Index and Google Scholar were searched for clinical studies recently published on P. multiflorum. Various clinical studies published articles were retrieved, providing information relevant to pharmacokinetics-pharmacodynamics analysis, sleep disorders, dyslipidemia treatment, and neurodegenerative diseases. This review is an effort to update the clinical picture of investigations ever carried on PMT and/or its isolated bio-compounds and to enlighten its therapeutic assessment. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4471648/ /pubmed/26130933 http://dx.doi.org/10.4103/0974-8490.157957 Text en Copyright: © Pharmacognosy Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Bounda, Guy-Armel
Feng, YU
spellingShingle Bounda, Guy-Armel
Feng, YU
Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds
author_facet Bounda, Guy-Armel
Feng, YU
author_sort Bounda, Guy-Armel
title Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds
title_short Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds
title_full Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds
title_fullStr Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds
title_full_unstemmed Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds
title_sort review of clinical studies of polygonum multiflorum thunb. and its isolated bioactive compounds
description Polygonum multiflorum Thunb. (PMT), officially listed in the Chinese Pharmacopoeia, is one of the most popular perennial Chinese traditional medicines known as He shou wu in China and East Asia, and as Fo-ti in North America. Mounting pharmacological studies have stressed out its key benefice for the treatment of various diseases and medical conditions such as liver injury, cancer, diabetes, alopecia, atherosclerosis, and neurodegenerative diseases as well. International databases such as PubMed/Medline, Science citation Index and Google Scholar were searched for clinical studies recently published on P. multiflorum. Various clinical studies published articles were retrieved, providing information relevant to pharmacokinetics-pharmacodynamics analysis, sleep disorders, dyslipidemia treatment, and neurodegenerative diseases. This review is an effort to update the clinical picture of investigations ever carried on PMT and/or its isolated bio-compounds and to enlighten its therapeutic assessment.
publisher Medknow Publications & Media Pvt Ltd
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471648/
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