Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds
Polygonum multiflorum Thunb. (PMT), officially listed in the Chinese Pharmacopoeia, is one of the most popular perennial Chinese traditional medicines known as He shou wu in China and East Asia, and as Fo-ti in North America. Mounting pharmacological studies have stressed out its key benefice for th...
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Medknow Publications & Media Pvt Ltd
2015
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pubmed-44716482015-07-01 Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds Bounda, Guy-Armel Feng, YU Review Article Polygonum multiflorum Thunb. (PMT), officially listed in the Chinese Pharmacopoeia, is one of the most popular perennial Chinese traditional medicines known as He shou wu in China and East Asia, and as Fo-ti in North America. Mounting pharmacological studies have stressed out its key benefice for the treatment of various diseases and medical conditions such as liver injury, cancer, diabetes, alopecia, atherosclerosis, and neurodegenerative diseases as well. International databases such as PubMed/Medline, Science citation Index and Google Scholar were searched for clinical studies recently published on P. multiflorum. Various clinical studies published articles were retrieved, providing information relevant to pharmacokinetics-pharmacodynamics analysis, sleep disorders, dyslipidemia treatment, and neurodegenerative diseases. This review is an effort to update the clinical picture of investigations ever carried on PMT and/or its isolated bio-compounds and to enlighten its therapeutic assessment. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4471648/ /pubmed/26130933 http://dx.doi.org/10.4103/0974-8490.157957 Text en Copyright: © Pharmacognosy Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Bounda, Guy-Armel Feng, YU |
spellingShingle |
Bounda, Guy-Armel Feng, YU Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds |
author_facet |
Bounda, Guy-Armel Feng, YU |
author_sort |
Bounda, Guy-Armel |
title |
Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds |
title_short |
Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds |
title_full |
Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds |
title_fullStr |
Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds |
title_full_unstemmed |
Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds |
title_sort |
review of clinical studies of polygonum multiflorum thunb. and its isolated bioactive compounds |
description |
Polygonum multiflorum Thunb. (PMT), officially listed in the Chinese Pharmacopoeia, is one of the most popular perennial Chinese traditional medicines known as He shou wu in China and East Asia, and as Fo-ti in North America. Mounting pharmacological studies have stressed out its key benefice for the treatment of various diseases and medical conditions such as liver injury, cancer, diabetes, alopecia, atherosclerosis, and neurodegenerative diseases as well. International databases such as PubMed/Medline, Science citation Index and Google Scholar were searched for clinical studies recently published on P. multiflorum. Various clinical studies published articles were retrieved, providing information relevant to pharmacokinetics-pharmacodynamics analysis, sleep disorders, dyslipidemia treatment, and neurodegenerative diseases. This review is an effort to update the clinical picture of investigations ever carried on PMT and/or its isolated bio-compounds and to enlighten its therapeutic assessment. |
publisher |
Medknow Publications & Media Pvt Ltd |
publishDate |
2015 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471648/ |
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1613237139315621888 |