iPSC-Based Models to Unravel Key Pathogenetic Processes Underlying Motor Neuron Disease Development
Motor neuron diseases (MNDs) are neuromuscular disorders affecting rather exclusively upper motor neurons (UMNs) and/or lower motor neurons (LMNs). The clinical phenotype is characterized by muscular weakness and atrophy leading to paralysis and almost invariably death due to respiratory failure. Ad...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
MDPI
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470174/ |