Metabonomic Evaluation of Chronic Unpredictable Mild Stress-Induced Changes in Rats by Intervention of Fluoxetine by HILIC-UHPLC/MS

Metabonomic Evaluation of Chronic Unpredictable Mild Stress-Induced Changes in Rats by Intervention of Fluoxetine by HILIC-UHPLC/MS

Hydrophilic interaction-ultra high performance liquid chromatography (HILIC-UHPLC) allows the analysis of highly polar metabolites, providing complementary information to reversed-phase (RP) chromatography. By optimization of the preparation and analytical conditions in HILIC mode, HILIC-UHPLC/MS wa...

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Bibliographic Details
Main Authors: Zhao, Longshan, Xiong, Zhili, Lu, Xiumei, Zheng, Shuning, Wang, Fang, Ge, Lin, Su, Guangyue, Yang, Jingyu, Wu, Chunfu
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469692/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469692/

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