miR-372 inhibits p62 in head and neck squamous cell carcinoma in vitro and in vivo

miR-372 inhibits p62 in head and neck squamous cell carcinoma in vitro and in vivo

Here we showed that exogenous miR-372 expression and knockdown of p62 (sequestosome1 or SQSTM1), both increased migration of head and neck squamous cell carcinoma (HNSCC) cells. p62 induced phase II detoxification enzyme NADPH quinone oxidoreductase 1 (NQO1), which decreased ROS levels and cell migr...

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Bibliographic Details
Main Authors: Yeh, Li-Yin, Liu, Chung-Ji, Wong, Yong-Kie, Chang, Christine, Lin, Shu-Chun, Chang, Kuo-Wei
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467422/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467422/

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