Androgen receptor non-nuclear regulation of prostate cancer cell invasion mediated by Src and matriptase

Castration-resistant prostate cancers still depend on nuclear androgen receptor (AR) function despite their lack of dependence on exogenous androgen. Second generation anti-androgen therapies are more efficient at blocking nuclear AR; however resistant tumors still develop. Recent studies indicate S...

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Bibliographic Details
Main Authors: Zarif, Jelani C., Lamb, Laura E., Schulz, Veronique S., Nollet, Eric A., Miranti, Cindy K.
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466655/