New strategies for targeting matrix metalloproteinases
The development of matrix metalloproteinase (MMP) inhibitors has often been frustrated by a lack of specificity and subsequent off-target effects. More recently, inhibitor design has considered secondary binding sites (exosites) to improve specificity. Small molecules and peptides have been develope...
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| Format: | Online |
| Language: | English |
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2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466128/ |