Changing the Face of Kynurenines and Neurotoxicity: Therapeutic Considerations

Kynurenines are the products of tryptophan metabolism. Among them, kynurenine and kynurenic acid are generally thought to have neuroprotective properties, while 3-hydroxykynurenine, 3-hydroxyanthranilic acid and quinolinic acid are considered neurotoxic. They participate in immunoregulation and infl...

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Bibliographic Details
Main Authors: Bohár, Zsuzsanna, Toldi, József, Fülöp, Ferenc, Vécsei, László
Format: Online
Language:English
Published: MDPI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463617/