Phospholipase C γ1 regulates early secretory trafficking and cell migration via interaction with p115
An siRNA screen is used to monitor changes in the structure of the Golgi apparatus and how these correlate with cell migration. A hit from this screen, PLCγ1, regulates cell migration in a manner independent of its catalytic activity but in a manner that depends on regulation of membrane traffic.
| Main Authors: | , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
The American Society for Cell Biology
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462944/ |