Molecular mechanisms regulating the hormone sensitivity of breast cancer

Breast cancer is a heterogeneous disease. Approximately 70% of breast cancers are estrogen receptor (ER) positive. Endocrine therapy has dramatically improved the prognosis of ER-positive breast cancer; however, many tumors exhibit de novo or acquired resistance to endocrine therapy. A thorough unde...

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Bibliographic Details
Main Authors: Tokunaga, Eriko, Hisamatsu, Yuichi, Tanaka, Kimihiro, Yamashita, Nami, Saeki, Hiroshi, Oki, Eiji, Kitao, Hiroyuki, Maehara, Yoshihiko
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462367/