Magnetic resonance imaging of folic acid-coated magnetite nanoparticles reflects tissue biodistribution of long-acting antiretroviral therapy

Regimen adherence, systemic toxicities, and limited drug penetrance to viral reservoirs are obstacles limiting the effectiveness of antiretroviral therapy (ART). Our laboratory’s development of the monocyte-macrophage-targeted long-acting nanoformulated ART (nanoART) carriage provides a novel opport...

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Bibliographic Details
Main Authors: Li, Tianyuzi, Gendelman, Howard E, Zhang, Gang, Puligujja, Pavan, McMillan, JoEllyn M, Bronich, Tatiana K, Edagwa, Benson, Liu, Xin-Ming, Boska, Michael D
Format: Online
Language:English
Published: Dove Medical Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461087/