Key Sites for P2X Receptor Function and Multimerization: Overview of Mutagenesis Studies on a Structural Basis
P2X receptors constitute a seven-member family (P2X1-7) of extracellular ATP-gated cation channels of widespread expression. Because P2X receptors have been implicated in neurological, inflammatory and cardiovascular diseases, they constitute promising drug targets. Since the first P2X cDNA sequence...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Bentham Science Publishers
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460280/ |