Targeting neoplastic B cells and harnessing microenvironment: the “double face” of ibrutinib and idelalisib
Tyrosine kinase inhibitors (TKIs) targeting signaling molecules downstream B cell receptor (BCR) are powerfully spreading in the therapeutic landscape of B cell lymphoproliferative disease, due to a manageable toxicity profile and encouraging clinical effectiveness. In particular, ibrutinib, previou...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459446/ |