Rapamycin protects against gentamicin-induced acute kidney injury via autophagy in mini-pig models

Gentamicin may cause acute kidney injury. The pathogenesis of gentamicin nephrotoxicity is unclear. Autophagy is a highly conserved physiological process involved in removing damaged or aged biological macromolecules and organelles from the cytoplasm. The role of autophagy in the pathogenesis of gen...

Full description

Bibliographic Details
Main Authors: Cui, Jing, Bai, Xue-Yuan, Sun, Xuefeng, Cai, Guangyan, Hong, Quan, Ding, Rui, Chen, Xiangmei
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459224/