Probing microtubule polymerisation state at single kinetochores during metaphase chromosome motion
Kinetochores regulate the dynamics of attached microtubule bundles (kinetochore-fibres, K-fibres) to generate the forces necessary for chromosome movements in mitosis. Current models suggest that poleward-moving kinetochores are attached to depolymerising K-fibres and anti-poleward-moving kinetochor...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
The Company of Biologists
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457160/ |