Probing microtubule polymerisation state at single kinetochores during metaphase chromosome motion

Kinetochores regulate the dynamics of attached microtubule bundles (kinetochore-fibres, K-fibres) to generate the forces necessary for chromosome movements in mitosis. Current models suggest that poleward-moving kinetochores are attached to depolymerising K-fibres and anti-poleward-moving kinetochor...

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Bibliographic Details
Main Authors: Armond, Jonathan W., Vladimirou, Elina, Erent, Muriel, McAinsh, Andrew D., Burroughs, Nigel J.
Format: Online
Language:English
Published: The Company of Biologists 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457160/