P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy

P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy

Septic encephalopathy (SE) is a critical factor determining sepsis mortality. Vascular inflammation is known to be involved in SE, but the molecular events that lead to the development of encephalopathy remain unclear. Using time-lapse in vivo two-photon laser scanning microscopy, we provide the fir...

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Bibliographic Details
Main Authors: Wang, Huan, Hong, Ling-Juan, Huang, Ji-Yun, Jiang, Quan, Tao, Rong-Rong, Tan, Chao, Lu, Nan-Nan, Wang, Cheng-Kun, Ahmed, Muhammad M, Lu, Ying-Mei, Liu, Zhi-Rong, Shi, Wei-Xing, Lai, En-Yin, Wilcox, Christopher S, Han, Feng
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456628/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456628/

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