Dominant Red Coat Color in Holstein Cattle Is Associated with a Missense Mutation in the Coatomer Protein Complex, Subunit Alpha (COPA) Gene

Dominant Red Coat Color in Holstein Cattle Is Associated with a Missense Mutation in the Coatomer Protein Complex, Subunit Alpha (COPA) Gene

Coat color in Holstein dairy cattle is primarily controlled by the melanocortin 1 receptor (MC1R) gene, a central determinant of black (eumelanin) vs. red/brown pheomelanin synthesis across animal species. The major MC1R alleles in Holsteins are Dominant Black (MC1RD) and Recessive Red (MC1Re). A no...

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Bibliographic Details
Main Authors: Dorshorst, Ben, Henegar, Corneliu, Liao, Xiaoping, Sällman Almén, Markus, Rubin, Carl-Johan, Ito, Shosuke, Wakamatsu, Kazumasa, Stothard, Paul, Van Doormaal, Brian, Plastow, Graham, Barsh, Gregory S., Andersson, Leif
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456281/

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