Eliminating bovine tuberculosis in cattle and badgers: insight from a dynamic model
Bovine tuberculosis (BTB) is a multi-species infection that commonly affects cattle and badgers in Great Britain. Despite years of study, the impact of badgers on BTB incidence in cattle is poorly understood. Using a two-host transmission model of BTB in cattle and badgers, we find that published da...
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| Format: | Online |
| Language: | English |
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The Royal Society
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455805/ |
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pubmed-4455805 |
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oai_dc |
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pubmed-44558052015-06-12 Eliminating bovine tuberculosis in cattle and badgers: insight from a dynamic model Brooks-Pollock, Ellen Wood, James L. N. Research Articles Bovine tuberculosis (BTB) is a multi-species infection that commonly affects cattle and badgers in Great Britain. Despite years of study, the impact of badgers on BTB incidence in cattle is poorly understood. Using a two-host transmission model of BTB in cattle and badgers, we find that published data and parameter estimates are most consistent with a system at the threshold of control. The most consistent explanation for data obtained from cattle and badger populations includes within-host reproduction numbers close to 1 and between-host reproduction numbers of approximately 0.05. In terms of controlling infection in cattle, reducing cattle-to-cattle transmission is essential. In some regions, even large reductions in badger prevalence can have a modest impact on cattle infection and a multi-stranded approach is necessary that also targets badger-to-cattle transmission directly. The new perspective highlighted by this two-host approach provides insight into the control of BTB in Great Britain. The Royal Society 2015-06-07 /pmc/articles/PMC4455805/ /pubmed/25972466 http://dx.doi.org/10.1098/rspb.2015.0374 Text en http://creativecommons.org/licenses/by/4.0/ © 2015 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Brooks-Pollock, Ellen Wood, James L. N. |
| spellingShingle |
Brooks-Pollock, Ellen Wood, James L. N. Eliminating bovine tuberculosis in cattle and badgers: insight from a dynamic model |
| author_facet |
Brooks-Pollock, Ellen Wood, James L. N. |
| author_sort |
Brooks-Pollock, Ellen |
| title |
Eliminating bovine tuberculosis in cattle and badgers: insight from a dynamic model |
| title_short |
Eliminating bovine tuberculosis in cattle and badgers: insight from a dynamic model |
| title_full |
Eliminating bovine tuberculosis in cattle and badgers: insight from a dynamic model |
| title_fullStr |
Eliminating bovine tuberculosis in cattle and badgers: insight from a dynamic model |
| title_full_unstemmed |
Eliminating bovine tuberculosis in cattle and badgers: insight from a dynamic model |
| title_sort |
eliminating bovine tuberculosis in cattle and badgers: insight from a dynamic model |
| description |
Bovine tuberculosis (BTB) is a multi-species infection that commonly affects cattle and badgers in Great Britain. Despite years of study, the impact of badgers on BTB incidence in cattle is poorly understood. Using a two-host transmission model of BTB in cattle and badgers, we find that published data and parameter estimates are most consistent with a system at the threshold of control. The most consistent explanation for data obtained from cattle and badger populations includes within-host reproduction numbers close to 1 and between-host reproduction numbers of approximately 0.05. In terms of controlling infection in cattle, reducing cattle-to-cattle transmission is essential. In some regions, even large reductions in badger prevalence can have a modest impact on cattle infection and a multi-stranded approach is necessary that also targets badger-to-cattle transmission directly. The new perspective highlighted by this two-host approach provides insight into the control of BTB in Great Britain. |
| publisher |
The Royal Society |
| publishDate |
2015 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455805/ |
| _version_ |
1613231870878679040 |