Expanding the chemical space for natural products by Aspergillus-Streptomyces co-cultivation and biotransformation

Actinomycetes and filamentous fungi produce a wide range of bioactive compounds, with applications as antimicrobials, anticancer agents or agrochemicals. Their genomes contain a far larger number of gene clusters for natural products than originally anticipated, and novel approaches are required to...

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Bibliographic Details
Main Authors: Wu, Changsheng, Zacchetti, Boris, Ram, Arthur F.J., van Wezel, Gilles P., Claessen, Dennis, Hae Choi, Young
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455117/