The fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome
Cryptic unstable transcripts (CUTs) are rapidly degraded by the nuclear exosome. However, the mechanism by which they are recognized and targeted to the exosome is not fully understood. Here we report that the MTREC complex, which has recently been shown to promote degradation of meiotic mRNAs and r...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Pub. Group
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455066/ |