An RPTPα/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctions

An RPTPα/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctions

The role of myosin IIB in junctional contractility and its mode of regulation are not well understood. It is demonstrated that junctional recruitment of myosin IIB requires the activation of a receptor-type protein tyrosine phosphatase alpha–Src family kinase–Rap1 pathway. This reinforces the concep...

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Bibliographic Details
Main Authors: Gomez, Guillermo A., McLachlan, Robert W., Wu, Selwin K., Caldwell, Benjamin J., Moussa, Elliott, Verma, Suzie, Bastiani, Michele, Priya, Rashmi, Parton, Robert G., Gaus, Katharina, Sap, Jan, Yap, Alpha S.
Format: Online
Language:English
Published: The American Society for Cell Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454173/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454173/

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