Dlg3 Trafficking and Apical Tight Junction Formation Is Regulated by Nedd4 and Nedd4-2 E3 Ubiquitin Ligases

Dlg3 Trafficking and Apical Tight Junction Formation Is Regulated by Nedd4 and Nedd4-2 E3 Ubiquitin Ligases

The Drosophila Discs large (Dlg) scaffolding protein acts as a tumor suppressor regulating basolateral epithelial polarity and proliferation. In mammals, four Dlg homologs have been identified; however, their functions in cell polarity remain poorly understood. Here, we demonstrate that the X-linked...

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Bibliographic Details
Main Authors: Van Campenhout, Claude A., Eitelhuber, Andrea, Gloeckner, Christian J., Giallonardo, Patrizia, Gegg, Moritz, Oller, Heide, Grant, Seth G.N., Krappmann, Daniel, Ueffing, Marius, Lickert, Heiko
Format: Online
Language:English
Published: Cell Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452538/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452538/

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