Surface plasmon-enhanced Ag/CuS nanocomposites for cancer treatment

Photothermal therapy (PTT) for cancer treatment is the use of heat between 41 and 45 °C to damage cancer cells. As a new type of transducer agent for PTT of cancer, CuS nanoparticles have several advantages. The most favorable features are the low cost, simple, and easy preparation and small size fo...

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Main Authors:	Yang, Chang, Ma, Lun, Zou, Xiaoju, Xiang, Guangya, Chen, Wei
Format:	Online
Language:	English
Published:	Springer Vienna 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452078/

id	pubmed-4452078
recordtype	oai_dc
spelling	pubmed-44520782015-06-09 Surface plasmon-enhanced Ag/CuS nanocomposites for cancer treatment Yang, Chang Ma, Lun Zou, Xiaoju Xiang, Guangya Chen, Wei Original Paper Photothermal therapy (PTT) for cancer treatment is the use of heat between 41 and 45 °C to damage cancer cells. As a new type of transducer agent for PTT of cancer, CuS nanoparticles have several advantages. The most favorable features are the low cost, simple, and easy preparation and small size for targeting. However, the CuS nanoparticle PTT efficacy needs to be improved for practical applications. In this study, the CuS nano-PTT efficiency is enhanced via the local field enhancement from Ag nanoparticle surface plasmon coupling. The results show that absorbance of CuS nanoparticles in Ag/CuS nanocomposites is enhanced about four times by Ag nanoparticle surface plasmon coupling. Consequently, the PTT efficacy is enhanced and a power of 0.6 W/cm2 with a 980-nm laser is sufficient for Ag/CuS nano-PTT activation for cancer treatment in vitro observations. Springer Vienna 2013-05-18 2013 /pmc/articles/PMC4452078/ /pubmed/26069503 http://dx.doi.org/10.1007/s12645-013-0039-2 Text en © Springer-Verlag Wien 2013
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Yang, Chang Ma, Lun Zou, Xiaoju Xiang, Guangya Chen, Wei
spellingShingle	Yang, Chang Ma, Lun Zou, Xiaoju Xiang, Guangya Chen, Wei Surface plasmon-enhanced Ag/CuS nanocomposites for cancer treatment
author_facet	Yang, Chang Ma, Lun Zou, Xiaoju Xiang, Guangya Chen, Wei
author_sort	Yang, Chang
title	Surface plasmon-enhanced Ag/CuS nanocomposites for cancer treatment
title_short	Surface plasmon-enhanced Ag/CuS nanocomposites for cancer treatment
title_full	Surface plasmon-enhanced Ag/CuS nanocomposites for cancer treatment
title_fullStr	Surface plasmon-enhanced Ag/CuS nanocomposites for cancer treatment
title_full_unstemmed	Surface plasmon-enhanced Ag/CuS nanocomposites for cancer treatment
title_sort	surface plasmon-enhanced ag/cus nanocomposites for cancer treatment
description	Photothermal therapy (PTT) for cancer treatment is the use of heat between 41 and 45 °C to damage cancer cells. As a new type of transducer agent for PTT of cancer, CuS nanoparticles have several advantages. The most favorable features are the low cost, simple, and easy preparation and small size for targeting. However, the CuS nanoparticle PTT efficacy needs to be improved for practical applications. In this study, the CuS nano-PTT efficiency is enhanced via the local field enhancement from Ag nanoparticle surface plasmon coupling. The results show that absorbance of CuS nanoparticles in Ag/CuS nanocomposites is enhanced about four times by Ag nanoparticle surface plasmon coupling. Consequently, the PTT efficacy is enhanced and a power of 0.6 W/cm2 with a 980-nm laser is sufficient for Ag/CuS nano-PTT activation for cancer treatment in vitro observations.
publisher	Springer Vienna
publishDate	2013
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452078/
_version_	1613230570044653568

Surface plasmon-enhanced Ag/CuS nanocomposites for cancer treatment

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