Mastication as a Stress-Coping Behavior
Exposure to chronic stress induces various physical and mental effects that may ultimately lead to disease. Stress-related disease has become a global health problem. Mastication (chewing) is an effective behavior for coping with stress, likely due to the alterations chewing causes in the activity o...
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| Format: | Online |
| Language: | English |
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Hindawi Publishing Corporation
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450283/ |
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pubmed-44502832015-06-18 Mastication as a Stress-Coping Behavior Kubo, Kin-ya Iinuma, Mitsuo Chen, Huayue Review Article Exposure to chronic stress induces various physical and mental effects that may ultimately lead to disease. Stress-related disease has become a global health problem. Mastication (chewing) is an effective behavior for coping with stress, likely due to the alterations chewing causes in the activity of the hypothalamic-pituitary-adrenal axis and autonomic nervous system. Mastication under stressful conditions attenuates stress-induced increases in plasma corticosterone and catecholamines, as well as the expression of stress-related substances, such as neurotrophic factors and nitric oxide. Further, chewing reduces stress-induced changes in central nervous system morphology, especially in the hippocampus and hypothalamus. In rodents, chewing or biting on wooden sticks during exposure to various stressors reduces stress-induced gastric ulcer formation and attenuates spatial cognitive dysfunction, anxiety-like behavior, and bone loss. In humans, some studies demonstrate that chewing gum during exposure to stress decreases plasma and salivary cortisol levels and reduces mental stress, although other studies report no such effect. Here, we discuss the neuronal mechanisms that underline the interactions between masticatory function and stress-coping behaviors in animals and humans. Hindawi Publishing Corporation 2015 2015-05-18 /pmc/articles/PMC4450283/ /pubmed/26090453 http://dx.doi.org/10.1155/2015/876409 Text en Copyright © 2015 Kin-ya Kubo et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Kubo, Kin-ya Iinuma, Mitsuo Chen, Huayue |
| spellingShingle |
Kubo, Kin-ya Iinuma, Mitsuo Chen, Huayue Mastication as a Stress-Coping Behavior |
| author_facet |
Kubo, Kin-ya Iinuma, Mitsuo Chen, Huayue |
| author_sort |
Kubo, Kin-ya |
| title |
Mastication as a Stress-Coping Behavior |
| title_short |
Mastication as a Stress-Coping Behavior |
| title_full |
Mastication as a Stress-Coping Behavior |
| title_fullStr |
Mastication as a Stress-Coping Behavior |
| title_full_unstemmed |
Mastication as a Stress-Coping Behavior |
| title_sort |
mastication as a stress-coping behavior |
| description |
Exposure to chronic stress induces various physical and mental effects that may ultimately lead to disease. Stress-related disease has become a global health problem. Mastication (chewing) is an effective behavior for coping with stress, likely due to the alterations chewing causes in the activity of the hypothalamic-pituitary-adrenal axis and autonomic nervous system. Mastication under stressful conditions attenuates stress-induced increases in plasma corticosterone and catecholamines, as well as the expression of stress-related substances, such as neurotrophic factors and nitric oxide. Further, chewing reduces stress-induced changes in central nervous system morphology, especially in the hippocampus and hypothalamus. In rodents, chewing or biting on wooden sticks during exposure to various stressors reduces stress-induced gastric ulcer formation and attenuates spatial cognitive dysfunction, anxiety-like behavior, and bone loss. In humans, some studies demonstrate that chewing gum during exposure to stress decreases plasma and salivary cortisol levels and reduces mental stress, although other studies report no such effect. Here, we discuss the neuronal mechanisms that underline the interactions between masticatory function and stress-coping behaviors in animals and humans. |
| publisher |
Hindawi Publishing Corporation |
| publishDate |
2015 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450283/ |
| _version_ |
1613229925351817216 |