Mass Spectral Profile for Rapid Differentiating Beta-Lactams from Their Ring-Opened Impurities

High performance liquid chromatography tandem mass spectrometry (HPLC MS) has been widely used for β-lactam antibiotics determination. However, its application to identify impurities of these frequently used drugs is not sufficient at present. In this job, characteristic profiles of the collision in...

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Bibliographic Details
Main Authors: Wang, Hecheng, Huang, Haiwei, Cao, Jin, Chui, Dehua, Xiao, Shengyuan
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450268/