Ecdysteroids Sensitize MDR and Non-MDR Cancer Cell Lines to Doxorubicin, Paclitaxel, and Vincristine but Tend to Protect Them from Cisplatin

Ecdysteroids, analogs of the insect molting hormone, are known for their various mild, nonhormonal bioactivities in mammals. Previously, we reported that less-polar ecdysteroids can modulate the doxorubicin resistance of a multidrug resistant (MDR) mouse lymphoma cell line expressing the human ABCB1...

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Bibliographic Details
Main Authors: Martins, Ana, Sipos, Péter, Dér, Katalin, Csábi, József, Miklos, Walter, Berger, Walter, Zalatnai, Attila, Amaral, Leonard, Molnár, Joseph, Szabó-Révész, Piroska, Hunyadi, Attila
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449901/