Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE)12345

An increasing recognition has emerged of the complexities of the global health agenda—specifically, the collision of infections and noncommunicable diseases and the dual burden of over- and undernutrition. Of particular practical concern are both 1) the need for a better understanding of the bidirec...

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Main Authors:	Raiten, Daniel J, Ashour, Fayrouz A Sakr, Ross, A Catharine, Meydani, Simin N, Dawson, Harry D, Stephensen, Charles B, Brabin, Bernard J, Suchdev, Parminder S, van Ommen, Ben
Format:	Online
Language:	English
Published:	American Society for Nutrition 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448820/

id	pubmed-4448820
recordtype	oai_dc
spelling	pubmed-44488202016-05-01 Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE)12345 Raiten, Daniel J Ashour, Fayrouz A Sakr Ross, A Catharine Meydani, Simin N Dawson, Harry D Stephensen, Charles B Brabin, Bernard J Suchdev, Parminder S van Ommen, Ben Supplement—Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE): Proceedings An increasing recognition has emerged of the complexities of the global health agenda—specifically, the collision of infections and noncommunicable diseases and the dual burden of over- and undernutrition. Of particular practical concern are both 1) the need for a better understanding of the bidirectional relations between nutritional status and the development and function of the immune and inflammatory response and 2) the specific impact of the inflammatory response on the selection, use, and interpretation of nutrient biomarkers. The goal of the Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE) is to provide guidance for those users represented by the global food and nutrition enterprise. These include researchers (bench and clinical), clinicians providing care/treatment, those developing and evaluating programs/interventions at scale, and those responsible for generating evidence-based policy. The INSPIRE process included convening 5 thematic working groups (WGs) charged with developing summary reports around the following issues: 1) basic overview of the interactions between nutrition, immune function, and the inflammatory response; 2) examination of the evidence regarding the impact of nutrition on immune function and inflammation; 3) evaluation of the impact of inflammation and clinical conditions (acute and chronic) on nutrition; 4) examination of existing and potential new approaches to account for the impact of inflammation on biomarker interpretation and use; and 5) the presentation of new approaches to the study of these relations. Each WG was tasked with synthesizing a summary of the evidence for each of these topics and delineating the remaining gaps in our knowledge. This review consists of a summary of the INSPIRE workshop and the WG deliberations. American Society for Nutrition 2015-05 2015-04-01 /pmc/articles/PMC4448820/ /pubmed/25833893 http://dx.doi.org/10.3945/jn.114.194571 Text en © 2015 American Society for Nutrition This is a free access article, distributed under terms (http://www.nutrition.org/publications/guidelines-and-policies/license/) that permit unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Raiten, Daniel J Ashour, Fayrouz A Sakr Ross, A Catharine Meydani, Simin N Dawson, Harry D Stephensen, Charles B Brabin, Bernard J Suchdev, Parminder S van Ommen, Ben
spellingShingle	Raiten, Daniel J Ashour, Fayrouz A Sakr Ross, A Catharine Meydani, Simin N Dawson, Harry D Stephensen, Charles B Brabin, Bernard J Suchdev, Parminder S van Ommen, Ben Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE)12345
author_facet	Raiten, Daniel J Ashour, Fayrouz A Sakr Ross, A Catharine Meydani, Simin N Dawson, Harry D Stephensen, Charles B Brabin, Bernard J Suchdev, Parminder S van Ommen, Ben
author_sort	Raiten, Daniel J
title	Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE)12345
title_short	Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE)12345
title_full	Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE)12345
title_fullStr	Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE)12345
title_full_unstemmed	Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE)12345
title_sort	inflammation and nutritional science for programs/policies and interpretation of research evidence (inspire)12345
description	An increasing recognition has emerged of the complexities of the global health agenda—specifically, the collision of infections and noncommunicable diseases and the dual burden of over- and undernutrition. Of particular practical concern are both 1) the need for a better understanding of the bidirectional relations between nutritional status and the development and function of the immune and inflammatory response and 2) the specific impact of the inflammatory response on the selection, use, and interpretation of nutrient biomarkers. The goal of the Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE) is to provide guidance for those users represented by the global food and nutrition enterprise. These include researchers (bench and clinical), clinicians providing care/treatment, those developing and evaluating programs/interventions at scale, and those responsible for generating evidence-based policy. The INSPIRE process included convening 5 thematic working groups (WGs) charged with developing summary reports around the following issues: 1) basic overview of the interactions between nutrition, immune function, and the inflammatory response; 2) examination of the evidence regarding the impact of nutrition on immune function and inflammation; 3) evaluation of the impact of inflammation and clinical conditions (acute and chronic) on nutrition; 4) examination of existing and potential new approaches to account for the impact of inflammation on biomarker interpretation and use; and 5) the presentation of new approaches to the study of these relations. Each WG was tasked with synthesizing a summary of the evidence for each of these topics and delineating the remaining gaps in our knowledge. This review consists of a summary of the INSPIRE workshop and the WG deliberations.
publisher	American Society for Nutrition
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448820/
_version_	1613229378745925632

Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE)12345

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