Promiscuity progression of bioactive compounds over time

In the context of polypharmacology, compound promiscuity is rationalized as the ability of small molecules to specifically interact with multiple targets. To study promiscuity progression of bioactive compounds in detail, nearly 1 million compounds and more than 5.2 million activity records were ana...

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Bibliographic Details
Main Authors: Hu, Ye, Jasial, Swarit, Bajorath, Jürgen
Format: Online
Language:English
Published: F1000Research 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448747/