Preclinical Evidences for an Antimanic Effect of Carvedilol

Oxidative imbalance, alterations in brain-derived neurotrophic factor (BDNF), and mitochondrial dysfunction are implicated in bipolar disorder (BD) pathophysiology and comorbidities, for example, cardiovascular conditions. Carvedilol (CVD), a nonselective beta-blocker widely used for the treatment o...

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Bibliographic Details
Main Authors: de Souza, Greicy Coelho, Gomes, Julia Ariana de S., de Góis Queiroz, Ana Isabelle, de Araújo, Maíra Morais, Cavalcante, Lígia Menezes, Machado, Michel de Jesus Souza, Monte, Aline Santos, de Lucena, David Freitas, Quevedo, João, Carvalho, André Ferrer, Macêdo, Danielle
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446493/