Neurovascular and neurometabolic derailment in aging and Alzheimer's disease

The functional and structural integrity of the brain requires local adjustment of blood flow and regulated delivery of metabolic substrates to meet the metabolic demands imposed by neuronal activation. This process—neurovascular coupling—and ensued alterations of glucose and oxygen metabolism—neurom...

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Bibliographic Details
Main Authors: Lourenço, Cátia F., Ledo, Ana, Dias, Cândida, Barbosa, Rui M., Laranjinha, João
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445047/