Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology

Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology

Human PIWI-interacting RNAs (piRNAs) are known to be expressed in germline cells, functionally silencing LINEs and SINEs. Their expression patterns in somatic tissues are largely uncharted. We analyzed 6,260 human piRNA transcriptomes derived from non-malignant and tumour tissues from 11 organs. We...

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Bibliographic Details
Main Authors: Martinez, Victor D., Vucic, Emily A., Thu, Kelsie L., Hubaux, Roland, Enfield, Katey S.S., Pikor, Larissa A., Becker-Santos, Daiana D., Brown, Carolyn J., Lam, Stephen, Lam, Wan L.
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444957/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444957/

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