Cardiac-Specific SOCS3 Deletion Prevents In Vivo Myocardial Ischemia Reperfusion Injury through Sustained Activation of Cardioprotective Signaling Molecules

Cardiac-Specific SOCS3 Deletion Prevents In Vivo Myocardial Ischemia Reperfusion Injury through Sustained Activation of Cardioprotective Signaling Molecules

Myocardial ischemia reperfusion injury (IRI) adversely affects cardiac performance and the prognosis of patients with acute myocardial infarction. Although myocardial signal transducer and activator of transcription (STAT) 3 is potently cardioprotective during IRI, the inhibitory mechanism responsib...

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Bibliographic Details
Main Authors: Nagata, Takanobu, Yasukawa, Hideo, Kyogoku, Sachiko, Oba, Toyoharu, Takahashi, Jinya, Nohara, Shoichiro, Minami, Tomoko, Mawatari, Kazutoshi, Sugi, Yusuke, Shimozono, Koutatsu, Pradervand, Sylvain, Hoshijima, Masahiko, Aoki, Hiroki, Fukumoto, Yoshihiro, Imaizumi, Tsutomu
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444323/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444323/

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