Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients

Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients

UDP-glucuronosyltransferases (UGTs), the most important enzymes in body detoxification and homeostasis maintaining, govern the glucuronidation reaction of various endogenous and environmental carcinogens. The metabolic function of UGTs can be severely influenced by hepatocellular carcinoma (HCC), th...

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Bibliographic Details
Main Authors: Lu, Linlin, Zhou, Juan, Shi, Jian, Peng, Xiao-juan, Qi, Xiao-xiao, Wang, Ying, Li, Fang-yuan, Zhou, Fu-Yuan, Liu, Liang, Liu, Zhong-Qiu
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444081/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444081/

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