Site-Specific Immunomodulator: A Novel Treatment for Crohn's Disease

We investigated the mechanism of action, safety, and efficacy of the Site-Specific Immunomodulator (SSI) QBECO, a novel immunotherapy for Crohn's disease (CD). Using human monocytic THP-1 cells, we demonstrate that SSI QBECO (derived from the common colon bacteria E. coli) activates macrophages...

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Bibliographic Details
Main Authors: Bressler, Brian, Bethel, Kevin P., Kleef, Ralf, Reynolds, Sophie L., Sutcliffe, Simon, Mullins, David W., Gunn, Hal
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443884/