Effects of APC De-Targeting and GAr Modification on the Duration of Luciferase Expression from Plasmid DNA Delivered to Skeletal Muscle

Effects of APC De-Targeting and GAr Modification on the Duration of Luciferase Expression from Plasmid DNA Delivered to Skeletal Muscle

Immune responses to expressed foreign transgenes continue to hamper progress of gene therapy development. Translated foreign proteins with intracellular location are generally less accessible to the immune system, nevertheless they can be presented to the immune system through both MHC Class I and C...

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Bibliographic Details
Main Authors: Subang, Maria C., Fatah, Rewas, Wu, Ying, Hannaman, Drew, Rice, Jason, Evans, Claire F., Chernajovsky, Yuti, Gould, David
Format: Online
Language:English
Published: Bentham Science Publishers 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443798/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443798/

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